The three most common types of skin cancer are:
- Melanoma: Begins in the cells that control the pigment of your skin, called melanocytes
- Basal cell carcinoma: Starts in the cells lining the bottom of the epidermis
- Squamous cell carcinoma: Starts in the cells lining the top of the epidermis
There is some evidence that topical application of cannabinoid-based medications may effectively treat melanoma. There are certainly cannabinoid receptors on the skin, and it seems that phytocannabinoids (plant cannabinoids) can potentially cause apoptosis of cancerous skin cells and return the skin to normal.
Meanwhile, some animal studies suggest that cannabinoids can be useful in the treatment of non-melanoma skin cancers, with selective CB2 receptor agonists such as THC and beta-caryophyllene potentially being particularly effective. There are CB1 and CB2 receptors present on tumors, and local cannabinoid receptor activation may induce regression of skin tumors and apoptosis of cancerous cells. However, more human studies are needed to understand cannabis’s effects on skin cancer.
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