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Explore A-Z conditions
Endometriosis
Moderate
Cannabis for Endometriosis
50% of those with endometriosis suffer from chronic pain, and 70% of those with endometriosis suffer from pain during menstruation, called dysmenorrhea. Around 25% of women with endometriosis have no symptoms at all. Endometriosis affects an estimated 10.8 million people globally, as of 2015. The uterus contains the reproductive system’s highest concentration of the endocannabinoid anandamide (AEA). Anandamide is analogous to THC, and taking THC may increase estrogen production, and cannabidiol (CBD) may bind to estrogen receptors. Cannabinoids may be useful in treating the chronic pain and anxiety associated with endometriosis.
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Animal Study
2
Human Trial
1
Laboratory Study
1
Meta-analysis
8
Total studies
Endometriosis
12
Positive
9 studies
75%
Inconclusive
3 studies
25%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
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- Antiproliferative Effects of Cannabinoid Agonists on Deep Infiltrating Endometriosis.
- Cannabidiol for the Management of Endometriosis and Chronic Pelvic Pain
- Effect of palmitoylethanolamide-polydatin combination on chronic pelvic pain associated with endometriosis: preliminary observations
- Endocannabinoid involvement in endometriosis.
- Illicit Cannabis Usage as a Management Strategy in New Zealand Women with Endometriosis: An Online Survey