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Known by some as “Double-Deuce,” the 22 strain (cultivar) is a sativa-leaning hybrid made by crossing OG Kush with Jack Herer. Diamond, tree-shaped buds, and tightly packed forest-green leaves are defining features of the 22 strain. 22 has sage, pine, and floral notes, with energetic, uplifting effects. 22 may help manage anxiety, depression, ADHD, PTSD, and chronic pain.

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Strain types

  • 30%Indica
  • 70%Sativa


  • Floral
  • Pine
  • Sage
  • Spicy


  • Chemical
  • Pine
  • Sage


  • Beta-Caryophyllene

  • Limonene

  • Myrcene



22s has been reported to have the following effects:

  • Creativity
  • Euphoria
  • Happiness
  • Talkative

The following adverse effects have also been reported:

  • Anxiety
  • Dry Eyes
  • Dry Mouth
  • Headache
  • Rapid Heartbeat
  • Thirst

The effects of the 22 strain are strong, fast-acting, and long-lasting.

Users of 22 report that the strain causes a cerebral high, leading to an uplifted mood. This then gives way to a much more relaxing and numbing full-body high. 22 is perfect for daytime use, whether you need to be productive, exercise, or feel more energized.

Medical Applications

The 22 strain can be used for medicinal and therapeutic purposes.
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Headache & Migraine

Cannabinoids like CBD can modulate serotonin transmission, which can help alleviate headaches as well as nausea, anxiety, and depression.

Organ Systems

  • Brain & Nervous System
Muscle Spasms

THC has sedative effects and acts as an anti-spasmodic. The addition of CBD increases THC’s ability to treat spasms.

Organ Systems

  • Brain & Nervous System
  • Muscular
Post-Traumatic Stress Disorder (PTSD)

Those with PTSD have elevated expression of CB1 receptors in the nervous system. Low to moderate doses of THC and moderate to high doses of CBD can help treat anxiety, insomnia, and low mood associated with PTSD.

Organ Systems

  • Mental / Emotional

Low doses of THC, moderate to high doses of CBD, and uplifting terpenes like limonene and pinene can help improve mood. THC and CBD can increase the amount of the bliss molecule, anandamide, available in the body, enhancing mood.

Organ Systems

  • Brain & Nervous System



growing strains

The 22 strain is moderately challenging to grow. It may not be the best choice for inexperienced users wishing to grow their cannabis.

22 has a large yield, owing to the parent strain Jack Herer. When 22 is grown outside, you can expect a yield of approximately 400 grams (14 ounces) of bud per plant. Indoors, 22 typically yields between 10.5 to 14 ounces (300 and 400 grams) of bud per square meter.


When grown indoors, 22 reaches heights between 30 and 60 inches (76 and 152 cm).

This strain can grow taller outdoors. When in optimal environmental conditions, it can grow to between 60 and 80 inches (152 to 203 cm). Due to these heights, it’s important to remember that the 22 strain needs a lot of space around it to grow.

Humidity and Temperature

Like many other cannabis strains, 22 grows best in conditions resembling a Mediterranean climate. A combination of sunshine, warmth, and humidity levels under 70% is optimal for growing 22 to its full potential.


The 22 strain usually flowers after around 60 to 70 days or about ten weeks. If it is grown outside, in the Northern Hemisphere, you can expect it to be ready to harvest sometime during October.

As a photoperiod strain, 22’s onset of flowering is influenced by changes in the light cycle, such as the hours of sunlight each day.

Frequently Asked Questions

What is the 22 strain good for?

How does the 22 strain make you feel?

22 produces an uplifting, cerebral high that has been reported to make people feel creative, euphoric, happy, and talkative.

Is 22 an indica or sativa?

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closeup of marijuana nug

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