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Cannabis for Uterine / Endometrial / Womb Cancer

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Last updated on Oct 7, 2024

Created on Jan 5, 2022

Endometrial cancer (sometimes also called uterine or womb cancer) is a type of cancer that begins in the layer of cells that form the lining (endometrium) of the uterus. Cervical cancer is a separate type of cancer. Adenocarcinoma cancers are the most common type of endometrial cancer. Common symptoms of endometrial cancer include pelvic pain, unusual vaginal bleeding and weight loss.

The two major endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), induce tumor cell death via interaction with the cannabinoid receptor, TRPV1. Treatment with a combination of anandamide and CBD showed particular promise in the treatment of endometrial cancer, but lab studies do not always translate to positive results in humans.

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Research Overview

Animal Study

1

Double Blind Clinical Trial

1

Laboratory Study

5

Meta-analysis

7

Total studies

Uterine / Endometrial / Womb Cancer

14

Positive

11 studies

79%

Inconclusive

2 studies

14%

Negative

1 studies

7%

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