Can You Use Weed If You Take Cyclobenzaprine, AKA Flexeril?

Using cannabis with cyclobenzaprine (Flexeril) may increase side effects such as dizziness, drowsiness, impaired thinking, confusion, and difficulty concentrating. Common side effects of cyclobenzaprine include headache, tiredness, dizziness, and dry mouth, and these adverse effects may increase in likelihood and severity by using cannabis.

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What Is Cyclobenzaprine?

Cyclobenzaprine is the generic name for Flexeril and Amrix. Cyclobenzaprine is in a class of medications called “skeletal muscle relaxants.”

Uses and How It Works

Cyclobenzaprine is an oral prescription medication used for muscle spasms from musculoskeletal conditions of sudden onset. It is often used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Cyclobenzaprine is not valuable for cerebral palsy.

Potential Benefits and Risks of Mixing Cannabis and Cyclobenzaprine

Potential Benefits

• Just like cyclobenzaprine, cannabis can help treat muscle spasms and sporting injuries.
• Common side effects of cyclobenzaprine include headache and fatigue, which medical cannabis can help relieve.

Potential Risks

• Cyclobenzaprine can have sedative effects that are increased when combined with cannabis.
• Dizziness, fatigue, and dry mouth may also exacerbate concurrent cannabis and cyclobenzaprine use.

The Bottom Line

Although mixing cannabis and cyclobenzaprine may not be deadly, using both together may increase the risk of suffering from adverse side effects such as headache, extreme tiredness, dizziness, loss of balance, and dry mouth. Those using both may need to reduce either their cannabis or their cyclobenzaprine use, and speaking to a doctor about this is the best option.