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7 Best Strains for Weight Loss

closeup pair of feet on a digital weighing scale

The best strains for weight loss tend to be sativa-dominant and contain high cannabinoid tetrahydrocannabivarin (THCV) levels. Cannabis research has shown that THCV may have the ability to suppress appetite and, as a result, help some people lose weight. Humulene is a terpene in cannabis associated with appetite suppression.

Discover the best marijuana strains for weight loss and learn why some strains are better than others for decreasing your appetite and preventing weight gain.

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How Cannabis Affects Weight Loss

Scientific studies have revealed that regular cannabis users have lower body mass index (BMI) figures than non-cannabis users. A lower BMI corresponds to lower levels of obesity and associated health conditions like heart disease and type 2 diabetes.

The way that cannabis may affect weight loss is through the cannabinoid THCV. In low to moderate doses, THCV may block CB1 receptors in the brain that control appetite. But in higher doses, THCV is psychoactive and could have some of the same effects as THC, including appetite stimulation. However, if you use a sativa-dominant strain high in cannabidiol (CBD) and lower in THC, you may experience appetite suppression, even with elevated THCV levels.

CBD on its own may also be useful in weight loss, as the cannabinoid has shown to accelerate the speed at which the body processes sugars. This mechanism, in turn, may lead to a faster and more efficient metabolism, thus encouraging weight loss.  

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Best Ways to Use Cannabis for Weight Loss

Smoking marijuana is notorious for leading to the munchies. But not every cannabis strain stimulates appetite; you can still be a regular user and experience the opposite effect. Smoking weed with high concentrations of THCV and lower to moderate THC levels may ward off an unwanted case of the munchies and make you feel less hungry. Furthermore, smoking marijuana has been linked to faster metabolisms in some people.  

Topical cannabis products may also be helpful for weight loss by suppressing your appetite. CBD products, in particular, may be useful for weight loss, as they contain only trace amounts of THC (0.3% maximum). CBD isolate products contain no THC and are the purest form of cannabinoid available.

You may also like to try a few drops of a CBD tincture or cannabis tincture placed under the tongue. But you’ll probably want to avoid high-calorie cannabis edibles if you’re trying to lose weight. There are, however, healthy alternatives to cannabis edibles, including the ever-popular pot brownie.  

Starting your day with a high-CBD, low-THC sativa strain is another good strategy if you want to lose weight. That way, you’ll tackle your appetite first thing in the morning, potentially feeling less hungry throughout the day.

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Best Strains for Weight Loss

Here are some of the most popular strains for losing weight, which is not guaranteed to help you shed pounds but may reduce your appetite.

Dutch Treat

Northern Lights and Haze come together to create Dutch Treat, a sweet-smelling strain with balanced effects. Dutch Treat may make you feel uplifted, euphoric, and less likely to binge on unhealthy foods.

Durban Poison

This popular strain is named after the port city of Durban in South Africa. It is one of the few pure sativa strains and contains high levels of THCV and terpene. Some users report a creative boost along with sporadic bursts of energy with Durban Poison.


Blend California Orange and Skunk-1, and you get Tangie, a potent sativa with an enticing tangerine aroma. Tangie is also a sativa with notable levels of the terpene myrcene and the ability to energize you.

Pineapple Purps

Although Pineapple Purps contains low CBD levels (around 1%), this 90% sativa has been hailed for fighting hunger pangs. Rich in THCV, Pineapple Purps has a mysterious origin, but its powerfully energizing effects are clear.  

Willie Nelson

Named for the American musician and bred with THCV content in mind, Willie Nelson is one of the best cannabis strains for marijuana users who want to lose weight. Sativa-dominant at 60%, Willie Nelson will infuse you with energy while potentially decreasing your appetite.

Jack the Ripper

Also called JTR, this sativa-dominant hybrid was named for the 19th-century London serial killer. Jack the Ripper has moderate levels of THC (up to 17%) and is reputed to have intense energizing effects.


Cannatonic has all the elements of a good weight loss strain: high CBD, low THC, and sativa dominance. A cross between MK Ultra and G13 Haze, Cannatonic is popular among users who want to avoid a strong psychoactive high while experiencing the many possible benefits of CBD.

Other humulene-rich varieties of cannabis that may help reduce hunger include Super Lemon Haze, Sour Diesel, and White Widow. Some Girl Scout Cookies (GSC) phenotypes may also contain high levels of THCV and humulene.

Integrate cannabis into your weight loss regimen with a medical marijuana card. Leafwell’s qualified physicians are here to help you quickly apply online.

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Frequently Asked Questions

Does sativa make you lose weight?

Sativa-strains from equatorial regions are generally higher in THCV, a cannabinoid that has been shown to suppress appetite. THCV has even been dubbed "diet weed" but should not be considered a miracle cure for weight loss. It is possible, however, that consuming sativa-dominant cannabis strains may suppress your appetite.

What strain is good for weight loss?

The best weight-loss strains include sativa-dominant hybrids like Durban Poison and Dutch Treat. Avoid indica hybrids with high THC content like Royal Cookies and Purple Queen, which have appetite-stimulating properties and may make you feel hungrier.

Is there a strain that suppresses appetite?

Any cannabis strain that contains high levels of THCV and lower levels of THC could have the ability to suppress appetite. Sativa-leaning strains with high levels of CBD, cannabigerol (CBG), limonene, and humulene may effectively suppress some people's appetite.

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