What Is Rutin? Guide to the Flavonoid
Article written by
Tina MagrabiSenior Content Writer
Content reviewed by
Dr. Lewis JasseyMedical Director - Pediatric Medicine
Rutin is a bioflavonoid with potent anti-inflammatory and antioxidant effects. The flavonoid is found in fruits and vegetables and serves a number of health purposes, from boosting collagen production to helping your body process vitamin C.
Learn about the other health benefits of rutin, along with the flavonoid’s connection to cannabis.
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What Is Rutin?
Rutin is a flavonoid or natural nutrient found in plants, including cannabis. Flavonoids like rutin have been found to have beneficial effects on health by reducing oxidative stress, an imbalance in the body that can lead to a host of diseases.
Bitter tasting and potent, rutin naturally occurs in the cannabis plant and plays a role in the flavor profile of different strains. Apples, citrus fruits and buckwheat contain dense concentrations of rutin. You may also consume high levels of rutin when eating figs and drinking green or black tea.
How Rutin Works in Cannabis
The flavonoids in cannabis give both pigment and flavor to the plant. Rutin is a crystallized yellow powder with a bitter flavor profile. Flavonoids like rutin influence how your senses perceive the cannabis product you are consuming.
More importantly, the flavonoid rutin infuses the cannabis plant with therapeutic potency. In combination with terpenes and cannabinoids, flavonoids create a synergistic entourage effect that maximizes any medicinal benefits. As these plant compounds work in partnership, they bind to receptors in your endocannabinoid system, connecting with one another and sending signals to heal.
Health Benefits and Uses
The possible health benefits and uses of rutin are numerous and involve many systems in the body, such as the cardiovascular system, digestive system and endocrine system. The following is a sampling of therapeutic uses for rutin:
Rutin and Cancer
Some scientific research has found that rutin could fight the growth and development of cancerous cells and tumors. Specifically, rutin may be beneficial for leukemia, colon cancer, and colorectal cancer by shrinking malignant tumors.
Rutin and Epilepsy
Cannabis has already proven to help some people with epilepsy, notably through the FDA-approved drug Epidiolex. Some of that benefit may be due to the anticonvulsant properties of rutin (and quercetin), which has been shown to reduce epileptic seizures without significant adverse effects.
Rutin and Arthritis
The anti-inflammatory properties of rutin may combat pain and inflammation from rheumatoid arthritis. Some research on animal models has demonstrated that rutin could play a role in fighting osteoarthritis as well.
Rutin and Cholesterol
High levels of cholesterol often precede heart disease and cardiovascular attacks. In some studies, rutin (and other citrus flavonoids) lowered total cholesterol levels and plasma triglycerides in animals. The takeaway is that rutin could enhance heart health and decrease the likelihood of cardiovascular disease developing.
Rutin and Varicose Veins
Cutting edge research published in 2021 reveals that rutin protects against varicose veins. The data, featured in the Journal of Food Biochemistry, also suggests that rutin could reduce internal bleeding and hemorrhoids.
These are just a handful of the potential therapeutic uses of rutin. The flavonoid has also been cited as a possible tool against strokes, diabetes and high blood pressure (hypertension). However, many of the studies involving rutin were conducted on animals, and clinical trials with humans are essential to fully understand the therapeutic potential of rutin.
Side Effects of Rutin
Despite the health benefits of rutin, side effects may also occur in some people, especially those who take the flavonoid as a dietary supplement. The side effects of rutin may include:
- Headache or stomach ache
- Blurry vision
- Elevated white blood cell count
- Rash or flushed skin
- Nervousness and changes in heartbeat
- Stiff muscles
Consult with your doctor before taking rutin supplements. Like most dietary supplements, rutin supplements have not received FDA approval. And remember: the best way to experience any plant compound is directly from the source.
Experience a rich variety of flavonoids and other plant nutrients like rutin with a medical marijuana card. Apply for your MMJ card through Leafwell’s online clinic today and get your passport to legally enjoy the potential health benefits of cannabis.
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Frequently Asked Questions
What is rutin good for?
Rutin may help prevent blood clots, reduce “bad” LDL cholesterol and improve blood circulation. The bioflavonoid may also work to fight varicose veins, sometimes called “spider veins.”
What foods are high in rutin?
Foods that are high in rutin include buckwheat, apples and citrus fruits like oranges and lemons. You may also speak with your doctor about taking rutin supplements if you have trouble incorporating these rutin-rich foods into your diet.
Does rutin have side effects?
Yes, some people may experience side effects from rutin and should not take the flavonoid in the form of dietary supplements. Pregnant women in particular should refrain from taking rutin supplements, as side effects such as upset stomach and changes in heart rhythm may occur.
