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Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)

Moderate

Cannabis for Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)

SCIs are thought to affect between 10.4 and 83 people per million every year. In North America, about 39 in every million people incur a traumatic SCI each year. Falls and other high impact injuries are common causes of SCIs, but people with arthritis or multiple sclerosis (MS) are also at high risk of SCIs.

Spinal cord diseases (SCDs) can include degenerative disc disease (DDD), Spinocerebellar Ataxia (SCA), spinal stenosis, tumors affecting the spine, and many more. Activation of CB1 receptors is associated with deficits in motor coordination, whereas CB1 receptor antagonists may help prevent and overcome such deficits, restoring balance to the ECS and (quite literally) balance to the body and one’s ability to move.

There are a number of endocannabinoid receptors on the spinal cord. Targeting these could help prevent further cell damage. CBD may help repair broken, fractured and porous bones, as the ECS has been shown to play a role in the regulation of bone metabolism and the formation of bones.

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Animal Study

12

Double Blind Human Trial

7

Human Trial

2

Meta-analysis

11

Total studies

Spinal Cord Injuries (SCIs) and Spinal Cord Diseases (SCDs)

32

Positive

28 studies

88%

Inconclusive

3 studies

9%

Negative

1 studies

3%

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