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Gastro-Esophagal Reflux Disease (GERD)

Moderate

Cannabis for Gastro-Esophagal Reflux Disease (GERD)

Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the tube connecting your mouth and stomach. Symptoms of GERD can include heartburn, chest pain, difficulty swallowing, regurgitation of food, chronic cough, disrupted sleep, nausea and vomiting. GERD is more likely to occur in those who are obese, pregnant, have a hiatal hernia, or suffer from connective tissue disorders such as scleroderma. Smoking, caffeine and alcohol are aggravating factors. Common treatments include a change in diet and the proton pump inhibitor (PPI), omeprazole.

As for medical cannabis as a treatment for GERD, the results are mixed. One animal study shows an 80% reduction in transient relaxations of the lower esophageal sphincter, whereas other case studies show that smoke of any type can make GERD worse. Eating the wrong foods may also contribute to GERD. However, medical cannabis taken as a tincture or edible may be helpful for treating nausea, vomiting, appetite loss and stomach aches associated with GERD.

Some irritable bowel disease (IBDs) and irritable bowel syndrome (IBS) may be mistaken for GERD, as well as complicate it if they are comorbid.

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Animal Study

5

Double Blind Human Trial

2

Laboratory Study

1

Meta-analysis

12

Total studies

Gastro-Esophagal Reflux Disease (GERD)

20

Positive

14 studies

70%

Inconclusive

3 studies

15%

Negative

3 studies

15%

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