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Fragile X Syndrome

Moderate

Cannabis for Fragile X Syndrome

Fragile X syndrome is a genetic disorder that can cause a range of developmental problems, most notably autism, learning disabilities and cognitive impairment. Affected individuals delayed development of speech and language by the age of 2. Males are more often affected than females.

Fragile X syndrome is associated with conditions like autism spectrum disorder (AUD), attention deficit disorder (ADD) and attention-deficit hyperactivity disorder (ADHD), and seizure disorders such as epilepsy. Fragile X syndrome is caused by a mutation in the FMR1 gene.

It is theorized that mutations in the FMR1 gene impairs neuronal excitability, meaning signals from the brain aren’t sent properly and/or are sent very slowly. Enhanced endocannabinoid signaling and anandamide production may help treat conditions associated with fragile X syndrome.

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Animal Study

7

Human Trial

1

Meta-analysis

3

Total studies

Fragile X Syndrome

11

Positive

11 studies

100%

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