50% of those with endometriosis suffer from chronic pain, and 70% of those with endometriosis suffer from pain during menstruation, called dysmenorrhea. Around 25% of women with endometriosis have no symptoms at all. Endometriosis affects an estimated 10.8 million people globally, as of 2015. The uterus contains the reproductive system’s highest concentration of the endocannabinoid anandamide (AEA). Anandamide is analogous to THC, and taking THC may increase estrogen production, and cannabidiol (CBD) may bind to estrogen receptors. Cannabinoids may be useful in treating the chronic pain and anxiety associated with endometriosis.
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