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Explore A-Z conditions
Constipation
Moderate
Cannabis for Constipation
Constipation is when you find it hard to move your bowels or you go to the toilet less often than usual. Around 16 out of 100 U.S. adults have constipation, and it is one of the most common digestive problems in the US.
Cannabinoids and the endocannabinoid system (ECS) are heavily involved in digestion and keeping the stomach in balance. Alongside the brain & spinal cord, the digestive system contains one of the largest concentrations of cannabinoid receptors in the human body. An out-of-balance ECS can cause digestive problems of all sorts, including both diarrhea and constipation. Cannabinoids can “reset” the digestive system. “In a nationally representative sample of U.S. adults, recent users of marijuana had 32% lower odds of constipation compared with past or never users.”
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Animal Study
1
Human Trial
2
Meta-analysis
6
Total studies
Constipation
9
Inconclusive
5 studies
56%
Positive
4 studies
44%
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Relevant studies
The information in our comprehensive A to Z encyclopedia comes from real scientific studies.
Uncover the detailed results of these studies and find out how effective medical marijuana is for dozens of conditions.
- 2-Arachidonoyl glycerol suppresses gastric emptying via the cannabinoid receptor 1-cholecystokinin signaling pathway in mice
- Cannabinoids and Gastrointestinal Motility: Pharmacology, Clinical Effects, and Potential Therapeutics in Humans
- Cannabis sativa subsp. sativa's pharmacological properties and health effects: A scoping review of current evidence
- Decreased enteric fatty acid amide hydrolase activity is associated with colonic inertia in slow transit constipation
- Endocannabinoids in the gastrointestinal tract