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<h2 id="medical-cannabis-for-the-treatment-of-diabetes">Medical Cannabis for the Treatment of Diabetes</h2>
<h3><strong>Definition</strong></h3>
<p>Diabetes mellitus (DM) is a group of metabolic disorders in which high blood-sugar levels over prolonged periods of time cause nerve damage. In diabetes, the pancreas either does not produce enough insulin, or the body not responding properly to the insulin produced.</p>
<h3><strong>Potential Efficacy / Quality of Evidence (Low, Average, High) of Medical Marijuana for Diabetes</strong></h3>
<p>Average &ndash; potentially high, with THCV and CBD being of particular use. Both phytocannabinoids may be particularly useful in preventing insulin resistance, maintaining a healthy body-mass index (BMI) and help reduce the pain associated with diabetic neuropathy, where peripheral nerves are damaged by long-term insulin resistance.</p>
<h3><strong>Cannabinoids, Terpenes/Terpenoids, Strains and Ratios that May Help</strong></h3>
<p><a href="https://leafwell.com/blog/tetrahydrocannabivarin-thcv-cannabinoid/" target="_blank" rel="noopener noreferrer">THCV</a> and <a href="https://leafwell.com/blog/how-does-cbd-work/" target="_blank" rel="noopener noreferrer">CBD</a> could prove to be very useful for diabetes patients.</p>
<p><a href="https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/myrcene" target="_blank" rel="noopener">Myrcene</a> may also be useful.</p>
<h4><strong>Medical Cannabis Pros</strong></h4>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349875/" target="_blank" rel="noopener">CBD and THCV</a> could help regulate glucose levels and prevent insulin resistance.</p>
<p>May improve carbohydrate metabolism, helping <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204468/" target="_blank" rel="noopener">control and maintain weight</a>.</p>
<p>Keep blood vessels open and improve circulation.</p>
<p>Topicals can be useful for preventing tingling sensations.</p>
<p><a href="https://www.nature.com/articles/nature14260.epdf?referrer_access_token=HJIa0IOyOsID1jaxpKo519RgN0jAjWel9jnR3ZoTv0N-r1DRMF8qph7cCVitKc-yg1gQ93uRHdXZOFLStzW6lGZDSzghWUS6ZAw9a6s6Mi25ZB44_BPOZGze34ISLh6q" target="_blank" rel="noopener">Cannabinoids may help sweet things taste more sweet</a>, and possibly even help reduce sugar intake as the desire for sweet things is satiated more quickly.</p>
<h4><strong>Medical Cannabis Cons</strong></h4>
<p>Getting hunger pangs could be useful for diabetics, but also not so useful at times.</p>
<p>Diabetes can negatively affect memory, perception and coordination, and so can <a href="https://leafwell.com/blog/what-is-thc-tetrahydrocannabinol/" target="_blank" rel="noopener noreferrer">THC</a> to some extent.</p>
<p>Getting dry or cotton mouth and eyes is common for diabetics &ndash; cannabis can make this aspect worse.</p>
<h5><strong>More About the Condition</strong></h5>
<p>There are three types of diabetes, including:</p>
<p>Type 1 Diabetes or Type 1 DM &ndash; . An <a href="https://leafwell.com/medical-conditions/autoimmune-disorders/" target="_blank" rel="noopener">autoimmune condition</a> where the pancreas cannot produce enough insulin. Type 1 diabetes seems to have a genetic component, and there are links with other autoimmune disorders such as Crohn&rsquo;s disease. Diabetic ketoacidosis is an unpleasant and sometimes even fatal side-effect of type-1 diabetes, which can cause nausea, vomiting and abdominal pain.</p>
<p><a href="https://leafwell.com/blog/marijuana-and-diabetes/" target="_blank" rel="noopener">Type 2 Diabetes or Type 2 DM</a> &ndash; The more common type of diabetes, most often caused by a bad diet and lack of exercise. In some instances, long-term use of steroids can cause steroid-induced diabetes. Type 2 diabetes involves insulin resistance. This is when cells fail to respond to insulin properly. A lack of insulin may also develop as the condition progresses.</p>
<p>Gestational Diabetes &ndash; a type of diabetes that develops in pregnant women who otherwise have no history of diabetes.</p>
<p>Symptoms of diabetes and high blood sugar include frequent urination, sugar found in the urine due to malabsorption of glucose, skin rashes called &ldquo;diabetic dermadromes&rdquo;, increased thirst and increased hunger. As of 2015, an estimated 415 million people worldwide have diabetes of some form of diabetes, with 90% of cases being Type 2 Diabetes, making it one of the world&rsquo;s most pressing health problems.</p>

<h6><strong>Quotes from Experts</strong></h6>
<p>&ldquo;Epidemiologic studies have found lower prevalence rates of obesity and diabetes mellitus in marijuana users compared with people who have never used marijuana, suggesting a relationship between cannabinoids and peripheral metabolic processes.&rdquo; Source: Penner EA, Buettner H, Mittleman MA. &lsquo;<a href="https://pubmed.ncbi.nlm.nih.gov/23684393/" target="_blank" rel="noopener">The impact of marijuana use on glucose, insulin, and insulin resistance among US adults</a>&lsquo; <em>Am J Med.</em> 2013 Jul;126(7):583-9. doi: 10.1016/j.amjmed.2013.03.002. Epub 2013 May 15. PMID: 23684393.</p>
<div data-highlight="rec-card" data-title="Get your medical marijuana card" data-image='{"id":"22430","altText":"","sourceUrl":"https:\/\/admin.leafwell.com\/app\/uploads\/2021\/10\/woman-rec-card.png","srcSet":false}'>Connect with a licensed physician online in minutes.</div>
<h6><strong>Case Studies &ndash; Patient Stories</strong></h6>

<p><a href="https://www.youtube.com/watch?v=0ygtX2nyexo" target="_blank" rel="noopener">A Doctor&rsquo;s Case for Medical Marijuana | TED Talk</a></p>


Diabetes

Decreased Libido

Degenerative Disc Disease (DDD)

Depression

Diabetic Neuropathy

Diarrhea

Disorders of the Skin and Subcutaneous Tissue

Disorders of the Synovium and Tendons

Domestic Abuse

Down Syndrome

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A cannabinoid type 2 (CB2) receptor agonist augments NOS-dependent responses of cerebral arterioles during type 1 diabetes

Acute effects of hemp protein consumption on glycemic and satiety control: results of two randomized crossover trials

A Novel Standardized Cannabis sativa L. Extract and Its Constituent Cannabidiol Inhibit Human Polymorphonuclear Leukocyte Functions

Antioxidative properties and inhibition of key enzymes relevant to type-2 diabetes and hypertension by essential oils from black pepper

A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men.

Cannabis for Diabetes

28

2

1

5

33

Diabetes

69

Positive

91%

Inconclusive

6%

Negative

3%