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No, cannabis is not legal for medical or adult use in American Samoa
Cannabis, medical or otherwise, is illegal throughout American Samoa.
Possession of any amount carries a mandatory $5000 fine and potentially up to 5 years in prison. Cannabis use is not uncommon on the island, and it is the most widely-used illicit drug on the market. Cannabis grows naturally on the island, with little import from other countries.
There are plans to legalize medical marijuana in American Samoa, but the COVID pandemic has held up this process. Even though marijuana grows in the wild in American Samoa (and could potentially provide a source of revenue for the island as well), the territory takes a relatively firm stance on cannabis products. This includes CBD (cannabidiol) products, considered “marijuana” in American Samoa, and is equally restricted.