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8 Best Hybrid Strains to Try in 2023

sativa and indica leaf, trophy on a purple/green gradient background

Hybrid strains are made by crossing sativa strains with indica strains. In fact, most cannabis strains are hybrids, as there are very few pure sativa or indica strains. In fact, the term “strains” is inaccurate, as even a particular variety from a specific part of the world can grow in both sativa-like and indica-like ways, depending on the environment it was grown in.

Sativa strains are known for their energizing effects, while indicas are known for being calming. The full picture is more complicated, but most people associate invigoration with sativas and relaxation with indicas. Then, what are the effects of hybrid strains that combine sativa and indica lineage? 

In the past, hybrid varieties of cannabis were thought to have both energizing and relaxing effects, usually followed by the other. However, as we now know, it’s what cannabinoids and terpenes are in the plant that counts when it comes to effect. “Sativa” and “indica” distinctions are meaningless regarding their effects.

Still, there is some value in looking at what varieties have been used to create a hybrid and what traits breeders look for when creating them. Learn more about hybrid cannabis strains as we present our top eight list for 2023. 

Which Strains Are Best For You?

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White Widow

White Widow has diverse global origins as the offspring of a Brazilian sativa and Indian indica. The hybrid contains a balanced cannabidiol (CBD) ratio to tetrahydrocannabinol (THC). This 1:1 ratio is ideal for many people and activates the synergistic entourage effect, which may exert potency over conditions like chronic pain and anxiety. 

Gorilla Glue 

Gorilla Glue is a powerhouse hybrid strain that also goes under Original Glue, Gorilla Glue #4, and GG4. Euphoria and deep relaxation likely affect this THC-heavy (20%) strain that has won multiple Cannabis Cup awards. Earthy and a bit sour, Gorilla Glue is a blend of Chem’s Sister, Sour Dubb, and Chocolate Diesel. 

OG Kush

The Sunshine State takes credit for developing OG Kush in the 1990s. Cultivators in Florida crossed Chemdawg, Lemon Thai, and Hindu Kush to create this high THC (18%) and no CBD (0%) strain. Lemony OG Kush produces a head high and stress-relieving effects on the body. 

Chiquita Banana

Fans of OG Kush might like Chiquita Banana, a potential option for people seeking deep therapeutic effects. Chiquita Banana crosses OG Kush with Banana, resulting in a motherlode of THC: 26%. Novices beware and avoid this strain (especially in the form of super-potent marijuana edibles). There’s not a drop of CBD in this hybrid, but there is a good amount of limonene, a terpene reported to have antioxidant and anti-inflammatory properties

Bruce Banner #3

Any cannabis strain named for a superhero’s alter ego must be potent, and Bruce Banner #3 definitely is. Not quite as THC-heavy as Chiquita Banana at 20%, this hybrid strain nonetheless packs a punch. Bred from OG Kush and Strawberry Diesel, Bruce Banner #3 is known for its fast-acting effects, which lean towards invigorating. This motivating strain is popular among consumers with a full plate of tasks. 

Sour Space Candy

Sour Space Candy makes a strong contender if you’re looking for a CBD-dominant hybrid. With a 16% concentration of CBD and just 1% THC, Sour Space Candy could relax you without getting you high. First bred in Oregon, the hybrid strain includes the parentage of Sour Tsunami and Early Resin Berry. Cannabis plants of this strain yield colorful buds and a slightly sour citrus profile. 

Cherry Pie

Breed Granddaddy Purple with F1 Durb, and you’ve got a hybrid strain that tastes like sweet and sour cherries. Some people attribute a case of the giggles to this euphoric strain, while others simply unwind with its balance of energizing and calming effects. The THC content is moderate (16%) but still high for a novice cannabis consumer

Skunk #1

Skunk #1 has a long history dating back to the 1970s. The hybrid is genetically diverse with a blend of origins, including Afghani, Acapulco Gold, and Colombian Gold. The munchies are a stereotypical effect of marijuana, but it’s no myth that Skunk #1 might make you crave a hearty snack. Along with euphoric energy, hunger is one of the most commonly reported effects of Skunk #1. 

Experience the benefits of hybrid strains with a medical marijuana card obtained through Leafwell. Our doctors are here to meet with you online in our virtual clinic and help you apply for your MMJ card today.

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Frequently Asked Questions

What is the strongest hybrid strain?

Bruce Banner #3 and Chiquita Banana are two of the strongest hybrid cannabis strains, as they have been developed with THC in mind. Hybrids are often developed with vigor, pest resistance, and cannabinoid content in mind, with many being developed specifically for their THC or CBD content. A strong hybrid strain is often characterized by high or mid-range THC content and many other cannabinoids and terpenes.

However, cannabis is a natural substance with lots of variation, so varieties that usually have moderate THC content may, on occasion, have high THC content.

Which strain is better, hybrid or indica?

The better strain is always the one that works better for you. Plus, it can be difficult to differentiate between hybrids and indicas; sometimes, there might be little-to-no difference. In fact, some indica-leaning strains like Wedding Cake and Girl Scout Cookies (GSC) fall under the hybrid umbrella because they are not pure. The same is true of many sativa strains, like Blue Dream, which is not 100% sativa. Experiment with different strains to see which helps you meet your health and wellness goals.

Should you try a hybrid strain if you’re a beginner?

If you’re a beginner, you might consider a CBD-dominant hybrid strain. Starting with a hybrid strain that tips more toward THC dominance can be risky and more likely to lead to side effects. Speak with a qualified budtender at a licensed dispensary to see which marijuana strain could work best for you as a beginner.

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